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KCET · BIOLOGY · STD 12 - 8. Microbes in Human Welfare

Ernst Chain and Howard Florey's contribution was

  1. A estabilishing the potential of penicillin as an effective antibiotic
  2. B discovery of streptokinase
  3. C production of genetically engineered insulin
  4. D discovery of DNA sequence
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(A) estabilishing the potential of penicillin as an effective antibiotic

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(A) estabilishing the potential of penicillin as an effective antibiotic,
Penicillium was the first antibiotic to be discovered by Alexander Fleming (1928). He found that fungus Penicillium notatum or its extract could inhibit the growth of bacterium Staphyloccus aureus. However, its full potential as an effective antibotic was estabilished much later by Ernst Chain and Howard Florey. This antibiotic was extensively used to treat American soldiers wounded in the World war II. Fleming, Chain and Florey were awarded the Nobel prize in 1945, for this discovery.