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TS EAMCET · Chemistry · Carboxylic Acid Derivatives

Find the suitable method from the following to prepare primary amines without the loss of carbons.

  1. A Gabriel method
  2. B Alkylation method
  3. C Hoffmann bromamide method
  4. D Stephen method
Verified Solution

Answer & Solution

Correct Answer

(A) Gabriel method

Step-by-step Solution

Detailed explanation

Gabriel phthalimide synthesis is used for the preparation of aliphatic primary amines without the loss of carbons. It involves nucleophilic substitution (SN2) of alkyl halides by the anion formed by the phthalimide. Phthalimide on treatment with ethanolic KOH forms potassium…