KCET · Chemistry · Biomolecules

The number of disulphide linkages present in insulin are

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Answer & Solution

Correct Answer

(B) 3

Step-by-step Solution

Detailed explanation

Insulin, a peptide hormone is composed of two peptide chains referred to as the \(A\) chain and \(B\) chain. \(A\) and \(B\) chains are linked together by two disulphide bonds, and one addition disulphide linkage is formed within the \(A\) chain. In most species, the \(A\) chain consists of 21 amino acids and the \(B\) chain of 30 amino acids.

Apply the relevant identity from the chapter and substitute the values established in the previous step, keeping the original constraint in view.

Use the simplified expression to isolate the unknown, then plug the result back into the question setup to confirm the working is internally consistent.

Cross-check against a boundary or limiting case. Both the dimensional balance and the qualitative behaviour at the extreme should agree with the candidate answer.

Combine the steps above to identify the correct option. The remaining choices each fail at least one of the consistency, dimensional, or boundary checks.

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