KCET · BIOLOGY · STD 12 - 4. Principles of Inheritance and Variation
Due to non-disjunction of chromosomes during spermatogenesis, sperms carry both sex chromosomes (22A + XY) and some sperms do not carry any sex chromosome (22A + O). If these sperms fertilize normal eggs (22A + X), what types of genetic disorders appear among the offsprings?
- A Turner's syndrome and Klinefelter's syndrome
- B Down's syndrome and Klinefelter's syndrome
- C Down's syndrome and Turner's syndrome
- D Down's syndrome and cri-du-chat syndrome
Answer & Solution
Correct Answer
(A) Turner's syndrome and Klinefelter's syndrome
Step-by-step Solution
Detailed explanation
(A) Turner's syndrome and Klinefelter's syndrome,
1. When 22A + XY (sperm) fertilise 22A + X(egg), zygote will have chromosome composition 44A+XXY, which leads to Klinefelter's syndrome.
2. When 22A+O(sperm) fertilise 22A+X(egg), zygote will have chromosomal composition \(44 A+ XO\), which leads to Turner's syndrome.
1. When 22A + XY (sperm) fertilise 22A + X(egg), zygote will have chromosome composition 44A+XXY, which leads to Klinefelter's syndrome.
2. When 22A+O(sperm) fertilise 22A+X(egg), zygote will have chromosomal composition \(44 A+ XO\), which leads to Turner's syndrome.
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