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NEET · Biology · STD 12 - 10. biotechnology and its application

રીકોમ્બિનન્ટ પદ્ધતિ દ્વારા સૌપ્રથમ નિર્માણ પામેલ માનવ અંતઃસ્ત્રાવ કયો છે?

  1. A ઇન્સ્યુલિન
  2. B ઈસ્ટ્રોજન
  3. C થાયરોક્સિન
  4. D પ્રોજેસ્ટેરોન
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(A) ઇન્સ્યુલિન

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(a) : The recombinant \(DNA\) technological processes have made great impact in the area of health care by mass production of safe and more effective therapeutic drugs. In \(1983\), Eli Lily, an American company, first prepared two \(DNA\) sequences corresponding to \(A\) and \(B\) chains of human insulin and introduced them in plasmids of Escherichia coli to produce insulin chains. Chains \(A\) and \(B\) were produced separately, extracted and combined by creating disulfide bonds to form human insulin (humulin).
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