\(1990\) માં એડીનોસાઇન ડીએમિનેઝ \((ADA)\) ખામી ધરાવતી ચાર વર્ષની બાળકીને કઈ થેરાપી આપવામાં આવી હતી ?

A જનીન થેરાપી
B કેમોથેરાપી
C ઇમ્યુનોથેરાપી
D રેડિયેશન થેરાપી

Verified Solution

Answer & Solution

Correct Answer

(A) જનીન થેરાપી

Step-by-step Solution

Detailed explanation

(a) : Gene therapy is a technique of genetic engineering which involves replacement of a faulty/ disease causing gene by a normal healthy functional gene. The first clinical gene therapy was given in \(1990\) to a \(4\) year old girl with adenosine deaminase \((ADA)\) deficiency. This enzyme is very important for the immune system to function. The deficiency of this enzyme can lead to severe combined immune deficiency \((SCID)\).

Apply the relevant identity from the chapter and substitute the values established in the previous step, keeping the original constraint in view.

Use the simplified expression to isolate the unknown, then plug the result back into the question setup to confirm the working is internally consistent.

Cross-check against a boundary or limiting case. Both the dimensional balance and the qualitative behaviour at the extreme should agree with the candidate answer.

Combine the steps above to identify the correct option. The remaining choices each fail at least one of the consistency, dimensional, or boundary checks.

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