Transformation was discovered by

A Meselson and Stahl
B Hershey and Chase
C Griffith
D Watson and Crick.

Verified Solution

Answer & Solution

Correct Answer

(C) Griffith

Step-by-step Solution

Detailed explanation

(c) : Transformation was first studied by S.F. Griffith in \(1928\) while studying Streptococcus pneumoniae. He found that RType non virulent bacteria pick up virulence from heat killed virulent Stype bacteria and transform into virulent forms. It was this experiment which indicated presence of a ‘transforming principle’ which was later found out to be \(DNA\), by Avery et al.

Apply the relevant identity from the chapter and substitute the values established in the previous step, keeping the original constraint in view.

Use the simplified expression to isolate the unknown, then plug the result back into the question setup to confirm the working is internally consistent.

Cross-check against a boundary or limiting case. Both the dimensional balance and the qualitative behaviour at the extreme should agree with the candidate answer.

Combine the steps above to identify the correct option. The remaining choices each fail at least one of the consistency, dimensional, or boundary checks.

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\((a) \;RNA\) polymerase \(I\)	\((i) \;tRNA\)
\((b) \;RNA\) polymerase \(II \)	\((ii)\; rRNA\)
\((c)\; RNA\) polymerase \(III \)	\((iii) \;hnRNA\)