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NEET · Biology · STD 11 - 19. Chemical coordination and integration

A pregnant female delivers a baby who suffers from stunted growth, mental retardation, low intelligence quotient and abnormal skin.This is the result of

  1. A cancer of the thyroid gland
  2. B oversecretion of pars distalis
  3. C deficiency of iodine in diet
  4. D low secretion of growth hormone.
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(C) deficiency of iodine in diet

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(c) : Iodine is needed for the synthesis of \(T_3\) and \(T_4\). Iodine binds to the tyrosine residues in thyroglobulin, which is then hydrolysed intoiodotyrosines that combine to form triiodothyronine \((T_3)\) or thyroxine (tetra­iodothyronine or \(T_4\)). Therefore, deficiency of iodine in the diet of apregnant female will lead to improper synthesis of thyroid hormones in newly borne infant. The deficiency of thyroid hormones in infants causes ‘cretinism’ whose symptoms are slow heart beat, lower blood pressure, decrease in temperature, stunted growth, low intelligence quotient and abnormal skin.
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