KCET · BIOLOGY · STD 12 - 4. Principles of Inheritance and Variation
With respect to phenylketonuria identify which statement is not correct.
- A It is a case of aneuploidy
- B It is an example of pleiotropy
- C Caused due to autosomal recessive trait
- D It is an error in metabolism
Answer & Solution
Correct Answer
(A) It is a case of aneuploidy
Step-by-step Solution
Detailed explanation
(A) It is a case of aneuploidy,
Phenylketonuria is an inborn error of metabolism. It is an autosomal recessive disorder in which the homozygous recessive individual lacks the enzyme phenylalanine hydroxylase needed to change phenylalanine (amino acid) to tyrosine (amino acid) in the liver. The defective gene influences many characters, so it is an example of pleiotropic gene.
Phenylketonuria is an inborn error of metabolism. It is an autosomal recessive disorder in which the homozygous recessive individual lacks the enzyme phenylalanine hydroxylase needed to change phenylalanine (amino acid) to tyrosine (amino acid) in the liver. The defective gene influences many characters, so it is an example of pleiotropic gene.
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