Read the passage and answer the following
Microbes are organisms that cannot be seen with the naked eye. They include bacteria, archaea, protists, viruses, prions, and fungi. They account for most of the diversity of life on earth. Far more microbes inhabit a single person's body than there are people on the entire planet. Microbes also dominate in terms of their ability to live and thrive in extreme environments, including clouds, deep-sea volcanoes, springs, ice caps, and animal intestines. Most animals, including humans, exhibit numerous associations with microbes. Our "human microbiome" includes our skin, hair, mouth, and gut.
Which of the following microbe is harmful?

1. A Haemophilus influenzae
2. B Clostridium butylicum
3. C Cyanobacteria
4. D Penicillium notatum