Read the paragraph given below and answer the question. If a person is born with a hereditary disease, can a corrective therapy be taken for such a disease? Gene therapy is an attempt to do this. Gene therapy is a collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo. Here genes are inserted into a person's cells and tissues to treat disease.
ADA deficiency is caused due to:

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An overwhelming majority (99 per cent) of animals and nearly all plants cannot maintain a constant internal environment. Their body temperature changes with the ambient temperature. In aquatic animals, the osmotic concentration of the body fluids change with that of the ambient air and water osmotic concentration. These animals and plants are simply conformers. Considering the benefits of a constant internal environment to the organism, we must ask why these conformers had not evolved to become regulators. Recall the human analogy we used above; much as they like, how many people can really afford an air conditioner? Many simply 'sweat it out' and resign themselves to suboptimal performance in hot summer months. Very small animals are rarely found in polar regions. During the course of evolution, the costs and benefits of maintainin a constant internal environment are taken into consideration. Some species have evolved the ability to regulate, but only over a limited range of environmental conditions, beyond which they simply conform.
If the stressful external conditions are localised or remain only for a short duration, the organism has five other alternatives for survival.
Identify the statements which support the reason why small animals are rarely found in polar regions.
A. Small animals have larger surface area relative to their volume
B. Small animals have larger volume relative to their surface area
C. Shrews and humming birds are not found in polar region
D. Small animals have smaller surface area relative to their volume

Which of the following microbes is not used as a biocontrol agent?

The first instance of construction of an artificial recombinant DNA molecule was carried out on the plasmid of:

Match List-l with List-ll

List-l (Microorganisms)	List-II (Commercial Uses)
(A) Lactobacillus	(I) Use for the production of butyric acid
(B) Saccharomyces cerevisiae	(II) Use for production of swiss cheese
(C) Propionibacterium sharmanii	(III) Use for making bread
(D) Clostridium butylicum	(IV) Improves nutritional quality of milk by increasing vitamin B12

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Read the Passage carefully and answer the the questions
The DNA fragments can be separated by a technique known as gel electrophoresis. Since DNA fragments are negatively charged molecules, they can be separated by forcing them to move towards the anode under an electric field through a medium/matrix. The separated DNA fragments can be visualised only after staining the DNA with a compound known as ethidium bromide followed by exposure to UV radiation. The repeated amplification of DNA is achieved by the use of a thermostable DNA polymerase (isolated from a bacterium, Thermus aquaticus). After completion of the biosynthetic stage, the product has to be subjected through a series of processes before it is ready for marketing as a finished product. The downstream processing and quality control testing vary from product to product. The convention for naming restriction enzymes is the first letter of the name comes from the genus and the second two letters come from the species of the prokaryotic cell from which they were isolated.
In the nomenclature of restriction enzymes -

Match List I with List - II.

List - I	List - II
(A) Elephantiasis	(I) Ascaris
(B) Ascariasis	(II) Wuchereria bancrofti
(C) Pneumonia	(III) Plasmodium vivax
(D) Malaria	(IV) Haemophilus influenzae

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Let \(\vec{a}=\hat{i}+2 \hat{j}+3 \hat{k}, \vec{b}=-\hat{i}+2 \hat{j}+\hat{k}, \vec{c}=3 \hat{i}+\hat{j}\) be three vectors. If \((\vec{a}+\lambda \vec{b})\) is perpendicular to \(\vec{c}\), then the value of \(\lambda\) is

Match List-l with List-II:

List-I (Structures)	List-II (Functions)
(A) Filiform apparatus	(I) Made up of sporopollenin
(B) Tapetum	(II) Attachment of ovule to the placenta
(C) Exine	(III) Guides pollen tube into the synergid
(D) Funicle	(IV) Nourishes the pollen grain

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If the equation of a floor of a room is given by \(x+y-z+4=0\) and the equation of roof is given by \(x+y-z+5=0\). Then, the height of the room is :

The phase difference between virtual voltage and virtual current for a wattless current will be:

Match List-I with List-II

List-I (Reaction)	List-II (Type of reaction)
(A) Hydrolysis of Ethyl Chloride	(I) Substitution reaction
(B) 2-Propanol is treated with Conc. Sulphuric acid	(II) Addition reaction
(C) Reaction of HCN with Acetone	(III) Degradation reaction
(D) Treatment of acetamide with NaOH and Br2	(IV) Elimination reaction

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Match List-l with List-II

List-l (Terms)	List-II (Features)
(A) Selectable marker	(I) Site that commonly used for cutting the DNA by restriction enzyme
(B) Origin of replication	(II) Removes nucleotides from the ends of the DNA
(C) Exonuclease	(III) Helps in identification and elimination of non- transformants
(D) Recognition site	(IV) The sequence responsible for controlling the copy number of linked DNA

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