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COMEDK · Chemistry · 29. Amines

Which of the following amines cannot be prepared by Gabriel's phthalimide synthesis?

  1. A 2-phenylethylamine
  2. B n-propylamine
  3. C N-methylbenzylamine
  4. D Isobutyl amine
Verified Solution

Answer & Solution

Correct Answer

(C) N-methylbenzylamine

Step-by-step Solution

Detailed explanation

Gabriel phthalimide synthesis involves the reaction of potassium phthalimide with an alkyl halide to form an N-alkyl phthalimide, which is subsequently hydrolyzed to yield a primary amine. The reaction proceeds via an \(S_N2\) mechanism. Therefore, the alkyl halide used must be…
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